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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP1 subtype' and Ligand = 'BDBM50454060'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))		BDBM50454060
PNG
(CHEMBL4208379)
Show SMILES C[C@@](O)(C\C=C\[C@H]1CCC(=O)[C@@H]1CCSc1nc(cs1)C(O)=O)CC1CCCC1 |r|
Show InChI InChI=1S/C22H31NO4S2/c1-22(27,13-15-5-2-3-6-15)11-4-7-16-8-9-19(24)17(16)10-12-28-21-23-18(14-29-21)20(25)26/h4,7,14-17,27H,2-3,5-6,8-13H2,1H3,(H,25,26)/b7-4+/t16-,17+,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at recombinant human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level measured at 3 secs time...

Bioorg Med Chem 26: 200-214 (2018)


Article DOI: 10.1016/j.bmc.2017.11.035
BindingDB Entry DOI: 10.7270/Q2FF3VZ5
More data for this
Ligand-Target Pair