Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP2 subtype' and Ligand = 'BDBM202325'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM202325 (US9540357, example 16 | US9540357, example 17) Show SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(c1)-c1ccc(Cl)cc1C(F)(F)F |r| Show InChI InChI=1S/C30H27ClF3NO4/c31-23-10-13-25(26(18-23)30(32,33)34)21-4-1-5-22(17-21)27(36)14-11-24-12-15-28(37)35(24)16-2-3-19-6-8-20(9-7-19)29(38)39/h1,4-11,13-14,17-18,24,27,36H,2-3,12,15-16H2,(H,38,39)/b14-11+/t24-,27?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	>-28.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair