Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM202331'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202331 (US9540357, example 20 | US9540357, example 21) Show SMILES Cc1cc(Cl)cc(C)c1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-20-17-26(32)18-21(2)30(20)25-7-3-6-24(19-25)28(34)14-12-27-13-15-29(35)33(27)16-4-5-22-8-10-23(11-9-22)31(36)37/h3,6-12,14,17-19,27-28,34H,4-5,13,15-16H2,1-2H3,(H,36,37)/b14-12+/t27-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	-41.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202331 (US9540357, example 20 | US9540357, example 21) Show SMILES Cc1cc(Cl)cc(C)c1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C31H32ClNO4/c1-20-17-26(32)18-21(2)30(20)25-7-3-6-24(19-25)28(34)14-12-27-13-15-29(35)33(27)16-4-5-22-8-10-23(11-9-22)31(36)37/h3,6-12,14,17-19,27-28,34H,4-5,13,15-16H2,1-2H3,(H,36,37)/b14-12+/t27-,28?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	955	-34.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair