Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM202460'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202460 (US9540357, example 32 | US9540357, example 33) Show SMILES Cc1cc(Cl)ccc1-c1ccc(s1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C28H28ClNO4S/c1-18-17-21(29)8-11-23(18)25-13-14-26(35-25)24(31)12-9-22-10-15-27(32)30(22)16-2-3-19-4-6-20(7-5-19)28(33)34/h4-9,11-14,17,22,24,31H,2-3,10,15-16H2,1H3,(H,33,34)/b12-9+/t22-,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	536	-35.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM202460 (US9540357, example 32 | US9540357, example 33) Show SMILES Cc1cc(Cl)ccc1-c1ccc(s1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C28H28ClNO4S/c1-18-17-21(29)8-11-23(18)25-13-14-26(35-25)24(31)12-9-22-10-15-27(32)30(22)16-2-3-19-4-6-20(7-5-19)28(33)34/h4-9,11-14,17,22,24,31H,2-3,10,15-16H2,1H3,(H,33,34)/b12-9+/t22-,24?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83E+3	-30.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Allergan, Inc. US Patent					Assay Description A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...				US Patent US9540357 (2017) BindingDB Entry DOI: 10.7270/Q24M92QQ
					More data for this Ligand-Target Pair