Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM453710'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM453710 (2-(9-Ethyl-6-fluoro-8-methyl-9H-carbazol-3-yl)-4-f...) Show SMILES CCn1c2ccc(cc2c2cc(F)cc(C)c12)-c1nc2c(F)c(ccc2n1CCOC)C(O)=O Show InChI InChI=1S/C26H23F2N3O3/c1-4-30-20-7-5-15(12-18(20)19-13-16(27)11-14(2)24(19)30)25-29-23-21(31(25)9-10-34-3)8-6-17(22(23)28)26(32)33/h5-8,11-13H,4,9-10H2,1-3H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description 5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...				US Patent US10730856 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QRT
					More data for this Ligand-Target Pair