Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50107279'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107279 (CHEMBL3600883) Show SMILES Cl.C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccc(cc1)C#N)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H27N3O4/c1-17(19-7-9-20(10-8-19)24(29)30)26-23(28)22-4-2-3-13-27(22)14-15-31-21-11-5-18(16-25)6-12-21/h5-12,17,22H,2-4,13-15H2,1H3,(H,26,28)(H,29,30)/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107279 (CHEMBL3600883) Show SMILES Cl.C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccc(cc1)C#N)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H27N3O4/c1-17(19-7-9-20(10-8-19)24(29)30)26-23(28)22-4-2-3-13-27(22)14-15-31-21-11-5-18(16-25)6-12-21/h5-12,17,22H,2-4,13-15H2,1H3,(H,26,28)(H,29,30)/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at recombinant human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP accumulation by scinti...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107279 (CHEMBL3600883) Show SMILES Cl.C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccc(cc1)C#N)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H27N3O4/c1-17(19-7-9-20(10-8-19)24(29)30)26-23(28)22-4-2-3-13-27(22)14-15-31-21-11-5-18(16-25)6-12-21/h5-12,17,22H,2-4,13-15H2,1H3,(H,26,28)(H,29,30)/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	621	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107279 (CHEMBL3600883) Show SMILES Cl.C[C@H](NC(=O)[C@H]1CCCCN1CCOc1ccc(cc1)C#N)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H27N3O4/c1-17(19-7-9-20(10-8-19)24(29)30)26-23(28)22-4-2-3-13-27(22)14-15-31-21-11-5-18(16-25)6-12-21/h5-12,17,22H,2-4,13-15H2,1H3,(H,26,28)(H,29,30)/t17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at EP4 receptor in LPS-stimulated human whole blood assessed as inhibition of PGE2-induced TNF-alpha reduction preincubated for 3...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair