Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50107282'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107282 (CHEMBL3600786) Show SMILES Cl.OC(=O)c1ccc(CNC(=O)[C@H]2CCCCN2CCOc2ccccc2)cc1 |r| Show InChI InChI=1S/C22H26N2O4/c25-21(23-16-17-9-11-18(12-10-17)22(26)27)20-8-4-5-13-24(20)14-15-28-19-6-2-1-3-7-19/h1-3,6-7,9-12,20H,4-5,8,13-16H2,(H,23,25)(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107282 (CHEMBL3600786) Show SMILES Cl.OC(=O)c1ccc(CNC(=O)[C@H]2CCCCN2CCOc2ccccc2)cc1 |r| Show InChI InChI=1S/C22H26N2O4/c25-21(23-16-17-9-11-18(12-10-17)22(26)27)20-8-4-5-13-24(20)14-15-28-19-6-2-1-3-7-19/h1-3,6-7,9-12,20H,4-5,8,13-16H2,(H,23,25)(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at recombinant human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP accumulation by scinti...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107282 (CHEMBL3600786) Show SMILES Cl.OC(=O)c1ccc(CNC(=O)[C@H]2CCCCN2CCOc2ccccc2)cc1 |r| Show InChI InChI=1S/C22H26N2O4/c25-21(23-16-17-9-11-18(12-10-17)22(26)27)20-8-4-5-13-24(20)14-15-28-19-6-2-1-3-7-19/h1-3,6-7,9-12,20H,4-5,8,13-16H2,(H,23,25)(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-PGE2 from recombinant human EP4 receptor expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50107282 (CHEMBL3600786) Show SMILES Cl.OC(=O)c1ccc(CNC(=O)[C@H]2CCCCN2CCOc2ccccc2)cc1 |r| Show InChI InChI=1S/C22H26N2O4/c25-21(23-16-17-9-11-18(12-10-17)22(26)27)20-8-4-5-13-24(20)14-15-28-19-6-2-1-3-7-19/h1-3,6-7,9-12,20H,4-5,8,13-16H2,(H,23,25)(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	899	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at EP4 receptor in LPS-stimulated human whole blood assessed as inhibition of PGE2-induced TNF-alpha reduction preincubated for 3...				Bioorg Med Chem Lett 25: 3176-8 (2015) Article DOI: 10.1016/j.bmcl.2015.05.091 BindingDB Entry DOI: 10.7270/Q2FX7C79
					More data for this Ligand-Target Pair