Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50156529'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50156529 (CHEMBL3794226) Show SMILES [H][C@]12C[C@@H](O)[C@H](COc3ccc(Cl)c(C)c3)[C@@]1([H])CC[C@@H](O2)c1ccc(o1)C(O)=O |r| Show InChI InChI=1S/C21H23ClO6/c1-11-8-12(2-4-15(11)22)26-10-14-13-3-5-17(28-20(13)9-16(14)23)18-6-7-19(27-18)21(24)25/h2,4,6-8,13-14,16-17,20,23H,3,5,9-10H2,1H3,(H,24,25)/t13-,14-,16-,17-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human EP4 receptor expressed in CHO cells assessed as cAMP level by HTRF assay				Bioorg Med Chem Lett 26: 2446-9 (2016) Article DOI: 10.1016/j.bmcl.2016.03.110 BindingDB Entry DOI: 10.7270/Q2H41T90
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