Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50333729'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333729 (5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(N)=O Show InChI InChI=1S/C27H27N3O4S2/c1-16-4-10-21(11-5-16)36(33,34)30-27(32)29-13-12-19-6-8-20(9-7-19)23-22-15-17(2)14-18(3)24(22)35-25(23)26(28)31/h4-11,14-15H,12-13H2,1-3H3,(H2,28,31)(H2,29,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333729 (5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(N)=O Show InChI InChI=1S/C27H27N3O4S2/c1-16-4-10-21(11-5-16)36(33,34)30-27(32)29-13-12-19-6-8-20(9-7-19)23-22-15-17(2)14-18(3)24(22)35-25(23)26(28)31/h4-11,14-15H,12-13H2,1-3H3,(H2,28,31)(H2,29,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	171	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Ratio of Ki for EP4 receptor to EP4 receptor in presence of 10% HSA				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50333729 (5,7-dimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)b...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCc1ccc(cc1)-c1c(sc2c(C)cc(C)cc12)C(N)=O Show InChI InChI=1S/C27H27N3O4S2/c1-16-4-10-21(11-5-16)36(33,34)30-27(32)29-13-12-19-6-8-20(9-7-19)23-22-15-17(2)14-18(3)24(22)35-25(23)26(28)31/h4-11,14-15H,12-13H2,1-3H3,(H2,28,31)(H2,29,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor in presence of 10% HSA				Bioorg Med Chem Lett 21: 734-7 (2011) Article DOI: 10.1016/j.bmcl.2010.11.118 BindingDB Entry DOI: 10.7270/Q22N52JP
					More data for this Ligand-Target Pair