Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50537007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50537007 (CHEMBL4527730) Show SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(C(O)=O)c(Cl)cc2n1CCOC Show InChI InChI=1S/C25H22ClN3O3/c1-3-28-21-7-5-4-6-16(21)17-12-15(8-9-22(17)28)24-27-20-13-18(25(30)31)19(26)14-23(20)29(24)10-11-32-2/h4-9,12-14H,3,10-11H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	751	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antagonist activity at human EP4R assessed as inhibition of agonist-induced cAMP production by fluorescent cAMP tracer cAMP-d2 based FRET assay				J Med Chem 62: 2541-2563 (2019) Article DOI: 10.1021/acs.jmedchem.8b01862 BindingDB Entry DOI: 10.7270/Q25H7KSB
					More data for this Ligand-Target Pair