BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM50472624'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 1/2


(RAT)		BDBM50472624
PNG
(CHEMBL62439)
Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C24H30ClNO3S/c1-23(2,3)20-14-16(15-21(22(20)27)24(4,5)6)13-19-11-12-26(30(19,28)29)18-9-7-17(25)8-10-18/h7-10,13-15,27H,11-12H2,1-6H3/b19-13+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a<1n/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.

J Med Chem 43: 2040-8 (2000)


Article DOI: 10.1021/jm9906015
BindingDB Entry DOI: 10.7270/Q2H134R8
More data for this
Ligand-Target Pair