Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM50501719'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501719 (CHEMBL4096719) Show SMILES Cc1cc(F)c(-c2c(Cl)ncn2-c2ccc(Cl)cc2)c(F)c1 |(15.62,-14.23,;14.16,-14.72,;13,-13.69,;11.54,-14.18,;10.39,-13.16,;11.24,-15.68,;9.78,-16.17,;9.3,-17.64,;10.21,-18.89,;7.79,-17.65,;7.29,-16.19,;8.53,-15.27,;8.51,-13.73,;9.84,-12.96,;9.83,-11.42,;8.49,-10.66,;8.48,-9.12,;7.16,-11.44,;7.18,-12.98,;12.39,-16.71,;12.07,-18.22,;13.85,-16.23,)| Show InChI InChI=1S/C16H10Cl2F2N2/c1-9-6-12(19)14(13(20)7-9)15-16(18)21-8-22(15)11-4-2-10(17)3-5-11/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
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