Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM50501723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50501723 (CHEMBL4080447) Show SMILES Fc1cccc(F)c1-c1cnc(Cl)n1-c1ccc(Cl)cc1 |(15.83,-12.6,;16.98,-13.62,;18.44,-13.13,;19.6,-14.16,;19.28,-15.67,;17.82,-16.15,;17.51,-17.66,;16.68,-15.12,;15.21,-15.61,;14.74,-17.08,;13.22,-17.09,;12.73,-15.63,;11.26,-15.17,;13.96,-14.71,;13.95,-13.17,;15.28,-12.4,;15.27,-10.86,;13.93,-10.1,;13.91,-8.56,;12.6,-10.88,;12.61,-12.42,)| Show InChI InChI=1S/C15H8Cl2F2N2/c16-9-4-6-10(7-5-9)21-13(8-20-15(21)17)14-11(18)2-1-3-12(14)19/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of COX-mediated PGD2/PGE2 production in arachidonic acid-stimulated RBL1 cells preincubated for 2 hrs followed by A23187 induction for 15 ...				J Med Chem 60: 5120-5145 (2017) Article DOI: 10.1021/acs.jmedchem.7b00475 BindingDB Entry DOI: 10.7270/Q21G0Q81
					More data for this Ligand-Target Pair