Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM153280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM153280 (1-Benzofuran-2-yl-3-(4-dimethylamino-naphthalen-1-...) Show SMILES CN(O)c1ccc(\C=C\C(=O)c2cc3ccccc3o2)c2ccccc12 Show InChI InChI=1S/C22H17NO3/c1-23(25)19-12-10-15(17-7-3-4-8-18(17)19)11-13-20(24)22-14-16-6-2-5-9-21(16)26-22/h2-14,25H,1H3/b13-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.27E+3	n/a	n/a	n/a	n/a	8.0	25
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz					Assay Description 100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...				Chem Biol Drug Des 85: 729-42 (2015) Article DOI: 10.1111/cbdd.12457 BindingDB Entry DOI: 10.7270/Q26W98TX
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