Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50349914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50349914 (CHEMBL1814723) Show SMILES CSc1ccc(cc1)-c1cc(CC2CCCC2=O)ccc1C(C)C([O-])=O Show InChI InChI=1S/C22H24O3S/c1-14(22(24)25)19-11-6-15(12-17-4-3-5-21(17)23)13-20(19)16-7-9-18(26-2)10-8-16/h6-11,13-14,17H,3-5,12H2,1-2H3,(H,24,25)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of human whole blood COX-1 assessed as production of TXB2 after 24 hrs by EIA				Bioorg Med Chem 19: 3299-311 (2011) Article DOI: 10.1016/j.bmc.2011.04.050 BindingDB Entry DOI: 10.7270/Q2NZ881Z
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