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Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50491244'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 1


(Ovis aries (Sheep))		BDBM50491244
PNG
(CHEMBL2380930)
Show SMILES [#6]C([#6])([#6])[#6]-1=[#6]\[#6](-[#6]=[#6](-[#6]-1=O)C([#6])([#6])[#6])=[#7]/[#7]-[#6](=O)-c1cccnc1 |c:7,t:4|
Show InChI InChI=1S/C20H25N3O2/c1-19(2,3)15-10-14(11-16(17(15)24)20(4,5)6)22-23-18(25)13-8-7-9-21-12-13/h7-12H,1-6H3,(H,23,25)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.86E+4n/an/an/an/an/an/a



Medical University of South Carolina

Curated by ChEMBL


Assay Description
Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...

Bioorg Med Chem 21: 2551-9 (2013)


Article DOI: 10.1016/j.bmc.2013.02.033
BindingDB Entry DOI: 10.7270/Q2H41VBV
More data for this
Ligand-Target Pair