Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM22976'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22976 (CHEMBL358222 | Meclofenamic acid derivative, 28 | ...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NOCc2ccccc2)c1Cl Show InChI InChI=1S/C21H18Cl2N2O2/c1-14-11-12-17(22)20(19(14)23)24-18-10-6-5-9-16(18)21(26)25-27-13-15-7-3-2-4-8-15/h2-12,24H,13H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University School of Medicine					Assay Description For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...				Proc Natl Acad Sci U S A 97: 925-30 (2000) Article DOI: 10.1073/pnas.97.2.925 BindingDB Entry DOI: 10.7270/Q2XP736G
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM22976 (CHEMBL358222 | Meclofenamic acid derivative, 28 | ...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NOCc2ccccc2)c1Cl Show InChI InChI=1S/C21H18Cl2N2O2/c1-14-11-12-17(22)20(19(14)23)24-18-10-6-5-9-16(18)21(26)25-27-13-15-7-3-2-4-8-15/h2-12,24H,13H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assay				Bioorg Med Chem Lett 12: 521-4 (2002) BindingDB Entry DOI: 10.7270/Q2BP0247
					More data for this Ligand-Target Pair