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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50049663'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin G/H synthase 2


(Homo sapiens (Human))		BDBM50049663
PNG
(4',5'-Difluoro-2'-(6-methyl-pyridin-3-yl)-biphenyl...)
Show SMILES Cc1ccc(cn1)-c1cc(F)c(F)cc1-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C18H14F2N2O2S/c1-11-2-3-13(10-22-11)16-9-18(20)17(19)8-15(16)12-4-6-14(7-5-12)25(21,23)24/h2-10H,1H3,(H2,21,23,24)
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Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Searle Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2

J Med Chem 39: 1846-56 (1996)


Article DOI: 10.1021/jm950878e
BindingDB Entry DOI: 10.7270/Q2Z89BGW
More data for this
Ligand-Target Pair