Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50365159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365159 (CHEMBL1950011) Show SMILES CCc1ccc2c(CC(O)=O)c([nH]c2c1)C(=O)c1cc(C)ccn1 Show InChI InChI=1S/C19H18N2O3/c1-3-12-4-5-13-14(10-17(22)23)18(21-15(13)9-12)19(24)16-8-11(2)6-7-20-16/h4-9,21H,3,10H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	414	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
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