Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50365164'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365164 (CHEMBL1950016) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2cc(Cl)c(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H12ClFN2O3/c1-8-2-3-20-14(4-8)17(24)16-10(6-15(22)23)9-5-12(19)11(18)7-13(9)21-16/h2-5,7,21H,6H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365164 (CHEMBL1950016) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2cc(Cl)c(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H12ClFN2O3/c1-8-2-3-20-14(4-8)17(24)16-10(6-15(22)23)9-5-12(19)11(18)7-13(9)21-16/h2-5,7,21H,6H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair