Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-1' and Ligand = 'BDBM50259649'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50259649 (CHEMBL4077282) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)NCCc1ccccc1)B(O)O |r| Show InChI InChI=1S/C23H32BN3O4/c1-17(2)15-21(24(30)31)27-22(28)20(16-19-11-7-4-8-12-19)26-23(29)25-14-13-18-9-5-3-6-10-18/h3-12,17,20-21,30-31H,13-16H2,1-2H3,(H,27,28)(H2,25,26,29)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of 20S proteasome in human HL60 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by fluorescence analy...				Eur J Med Chem 125: 925-939 (2017) Article DOI: 10.1016/j.ejmech.2016.10.023 BindingDB Entry DOI: 10.7270/Q2348NTK
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