Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM446608'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM446608 (US10669289, Compound 15) Show SMILES CN(CC(=O)N[C@@H](Cc1ccc(C)cc1C)B(O)O)S(=O)(=O)C=C |r| Show InChI InChI=1S/C15H23BN2O5S/c1-5-24(22,23)18(4)10-15(19)17-14(16(20)21)9-13-7-6-11(2)8-12(13)3/h5-8,14,20-21H,1,9-10H2,2-4H3,(H,17,19)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MERCK PATENT GMBH US Patent					Assay Description Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immuno proteasome (0.25 nM) and s...				US Patent US10669289 (2020) BindingDB Entry DOI: 10.7270/Q2ZS30MF
					More data for this Ligand-Target Pair