Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM50516208'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50516208 (CHEMBL4471926) Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CC(=O)NC(C)(C)C)C(=O)NCCNC(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H35N5O5S/c1-18-10-12-20(13-11-18)36(34,35)30-21(16-22(31)29-25(2,3)4)23(32)26-14-15-27-24(33)28-17-19-8-6-5-7-9-19/h5-13,21,30H,14-17H2,1-4H3,(H,26,32)(H,29,31)(H2,27,28,33)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medicine Curated by ChEMBL					Assay Description Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrate				J Med Chem 62: 6137-6145 (2019) Article DOI: 10.1021/acs.jmedchem.9b00363 BindingDB Entry DOI: 10.7270/Q2862KTQ
					More data for this Ligand-Target Pair