Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM50516225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50516225 (CHEMBL4521524) Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CC(=O)NC(C)(C)C)C(=O)NCCNC(=O)c1cc(ccc1F)-c1ccccc1F |r| Show InChI InChI=1S/C30H34F2N4O5S/c1-19-9-12-21(13-10-19)42(40,41)36-26(18-27(37)35-30(2,3)4)29(39)34-16-15-33-28(38)23-17-20(11-14-25(23)32)22-7-5-6-8-24(22)31/h5-14,17,26,36H,15-16,18H2,1-4H3,(H,33,38)(H,34,39)(H,35,37)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hangzhou Xixi Hospital Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by cell based assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111646 BindingDB Entry DOI: 10.7270/Q2154MHB
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50516225 (CHEMBL4521524) Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CC(=O)NC(C)(C)C)C(=O)NCCNC(=O)c1cc(ccc1F)-c1ccccc1F |r| Show InChI InChI=1S/C30H34F2N4O5S/c1-19-9-12-21(13-10-19)42(40,41)36-26(18-27(37)35-30(2,3)4)29(39)34-16-15-33-28(38)23-17-20(11-14-25(23)32)22-7-5-6-8-24(22)31/h5-14,17,26,36H,15-16,18H2,1-4H3,(H,33,38)(H,34,39)(H,35,37)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medicine Curated by ChEMBL					Assay Description Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrate				J Med Chem 62: 6137-6145 (2019) Article DOI: 10.1021/acs.jmedchem.9b00363 BindingDB Entry DOI: 10.7270/Q2862KTQ
					More data for this Ligand-Target Pair