Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-8' and Ligand = 'BDBM50516229'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50516229 (CHEMBL4537720) Show SMILES CC(C)c1cccc(c1)C(=O)NCCNC(=O)[C@H](CC(=O)NC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C27H38N4O5S/c1-18(2)20-8-7-9-21(16-20)25(33)28-14-15-29-26(34)23(17-24(32)30-27(4,5)6)31-37(35,36)22-12-10-19(3)11-13-22/h7-13,16,18,23,31H,14-15,17H2,1-6H3,(H,28,33)(H,29,34)(H,30,32)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medicine Curated by ChEMBL					Assay Description Inhibition of human beta5 20S immunoproteasome using Ac-ANW-AMC as substrate				J Med Chem 62: 6137-6145 (2019) Article DOI: 10.1021/acs.jmedchem.9b00363 BindingDB Entry DOI: 10.7270/Q2862KTQ
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