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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Tat' and Ligand = 'BDBM50407489'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Tat


(Human immunodeficiency virus type 1 (isolate PCV12...)		BDBM50407489
PNG
(CHEMBL111424)
Show SMILES CC1(C)CC(C(=O)Nc2c(Cl)cccc2Cl)C(=O)C2OC12
Show InChI InChI=1S/C15H15Cl2NO3/c1-15(2)6-7(11(19)12-13(15)21-12)14(20)18-10-8(16)4-3-5-9(10)17/h3-5,7,12-13H,6H2,1-2H3,(H,18,20)
PDB
MMDB

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PubMed
n/an/a 3.17E+4n/an/an/an/an/an/a



Sterling Winthrop Pharmaecuticals Research Division

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of HIV-1 replication in SW480 cells using HIV tat assay

J Med Chem 38: 3197-206 (1995)


BindingDB Entry DOI: 10.7270/Q27D2WBX
More data for this
Ligand-Target Pair