BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Wnt-3a' and Ligand = 'BDBM374904'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374904
PNG
(US10251893, Cpd 112)
Show SMILES FC(F)(F)c1cc(CC(=O)Nc2ccc(cn2)-c2ccccn2)ccc1-c1ccnnc1
Show InChI InChI=1S/C23H16F3N5O/c24-23(25,26)19-11-15(4-6-18(19)16-8-10-29-30-14-16)12-22(32)31-21-7-5-17(13-28-21)20-3-1-2-9-27-20/h1-11,13-14H,12H2,(H,28,31,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair