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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Wnt-3a' and Ligand = 'BDBM374985'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))		BDBM374985
PNG
(2-(3-cyano-4-(2-methylpyridin-4-yl)phenyl)-N-(5-(p...)
Show SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cn2)-c2cccnn2)cc1C#N
Show InChI InChI=1S/C24H18N6O/c1-16-11-18(8-10-26-16)21-6-4-17(12-20(21)14-25)13-24(31)29-23-7-5-19(15-27-23)22-3-2-9-28-30-22/h2-12,15H,13H2,1H3,(H,27,29,31)
PDB

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PC cid
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UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



St. Jude Research Hospital



Assay Description
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...

J Med Chem 50: 5727-34 (2007)


BindingDB Entry DOI: 10.7270/Q2GM89KJ
More data for this
Ligand-Target Pair