Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 1 [11-371]' and Ligand = 'BDBM50130931'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50130931 (CHEMBL3633188) Show SMILES CC(C)(C)OC(=O)Nc1ccc(Nc2ncnc(Nc3ccc(cc3)C(N)=N)c2[N+]([O-])=O)cc1 Show InChI InChI=1S/C22H24N8O4/c1-22(2,3)34-21(31)29-16-10-8-15(9-11-16)28-20-17(30(32)33)19(25-12-26-20)27-14-6-4-13(5-7-14)18(23)24/h4-12H,1-3H3,(H3,23,24)(H,29,31)(H2,25,26,27,28)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assay				Bioorg Med Chem Lett 25: 5449-53 (2015) Article DOI: 10.1016/j.bmcl.2015.06.095 BindingDB Entry DOI: 10.7270/Q2R2136F
					More data for this Ligand-Target Pair