Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM176873'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM176873 (US10307413, Compound 45 | US10391089, Compound 45 ...) Show SMILES OC(CNC(=O)c1cccc(NC2CCOC2)c1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C23H29N3O3/c27-22(15-26-10-8-17-4-1-2-5-19(17)14-26)13-24-23(28)18-6-3-7-20(12-18)25-21-9-11-29-16-21/h1-7,12,21-22,25,27H,8-11,13-16H2,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US9675614 (2017) BindingDB Entry DOI: 10.7270/Q2MW2F9B
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM176873 (US10307413, Compound 45 | US10391089, Compound 45 ...) Show SMILES OC(CNC(=O)c1cccc(NC2CCOC2)c1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C23H29N3O3/c27-22(15-26-10-8-17-4-1-2-5-19(17)14-26)13-24-23(28)18-6-3-7-20(12-18)25-21-9-11-29-16-21/h1-7,12,21-22,25,27H,8-11,13-16H2,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10980794 (2021) BindingDB Entry DOI: 10.7270/Q25X2D23
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM176873 (US10307413, Compound 45 | US10391089, Compound 45 ...) Show SMILES OC(CNC(=O)c1cccc(NC2CCOC2)c1)CN1CCc2ccccc2C1 Show InChI InChI=1S/C23H29N3O3/c27-22(15-26-10-8-17-4-1-2-5-19(17)14-26)13-24-23(28)18-6-3-7-20(12-18)25-21-9-11-29-16-21/h1-7,12,21-22,25,27H,8-11,13-16H2,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				J Med Chem 52: 3073-83 (2009) BindingDB Entry DOI: 10.7270/Q2ZG6VMT
					More data for this Ligand-Target Pair