Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM297741'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297741 (1-(3-((cyclopentylamino)methyl)phenoxy)-3-(isoindo...) Show SMILES OC(COc1cccc(CNC2CCCC2)c1)CN1Cc2ccccc2C1 Show InChI InChI=1S/C23H30N2O2/c26-22(16-25-14-19-7-1-2-8-20(19)15-25)17-27-23-11-5-6-18(12-23)13-24-21-9-3-4-10-21/h1-2,5-8,11-12,21-22,24,26H,3-4,9-10,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description General Materials.S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), bicine, KCl, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG)...				US Patent US9732072 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VGW
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297741 (1-(3-((cyclopentylamino)methyl)phenoxy)-3-(isoindo...) Show SMILES OC(COc1cccc(CNC2CCCC2)c1)CN1Cc2ccccc2C1 Show InChI InChI=1S/C23H30N2O2/c26-22(16-25-14-19-7-1-2-8-20(19)15-25)17-27-23-11-5-6-18(12-23)13-24-21-9-3-4-10-21/h1-2,5-8,11-12,21-22,24,26H,3-4,9-10,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10118918 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZK6
					More data for this Ligand-Target Pair