Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM337145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM337145 (US9745291, Compound 191 | US9765068, Compound 191) Show SMILES CN(C)CCN(C)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r| Show InChI InChI=1S/C25H36N4O5S/c1-27(2)14-15-28(3)35(32,33)24-11-7-6-10-23(24)34-19-25(31)26-16-22(30)18-29-13-12-20-8-4-5-9-21(20)17-29/h4-11,22,30H,12-19H2,1-3H3,(H,26,31)/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...				US Patent US9765068 (2017) BindingDB Entry DOI: 10.7270/Q2959KN3
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