Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM451199'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM451199 (US10709709, Example 25) Show SMILES Nc1ncnc2n(cc(F)c12)[C@@H]1C[C@H]([C@H](O)c2ccc(F)cc2)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C18H18F2N4O3/c19-9-3-1-8(2-4-9)14(25)10-5-12(16(27)15(10)26)24-6-11(20)13-17(21)22-7-23-18(13)24/h1-4,6-7,10,12,14-16,25-27H,5H2,(H2,21,22,23)/t10-,12-,14-,15-,16+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...				US Patent US10709709 (2020) BindingDB Entry DOI: 10.7270/Q26113CC
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