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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM451268'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM451268
PNG
(US10709709, Example 95)
Show SMILES Cc1ncnc2n(ccc12)[C@@H]1C[C@H](Oc2cncc3CCNCc23)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C20H23N5O3/c1-11-13-3-5-25(20(13)24-10-23-11)15-6-16(19(27)18(15)26)28-17-9-22-7-12-2-4-21-8-14(12)17/h3,5,7,9-10,15-16,18-19,21,26-27H,2,4,6,8H2,1H3/t15-,16+,18+,19-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...

US Patent US10709709 (2020)


BindingDB Entry DOI: 10.7270/Q26113CC
More data for this
Ligand-Target Pair