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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM451281'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM451281
PNG
(US10709709, Example 108)
Show SMILES Nc1ncnc2n(cc(F)c12)[C@@H]1C[C@H](Oc2cc(Cl)c(F)c3CCNCc23)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C20H20ClF2N5O3/c21-10-3-13(9-5-25-2-1-8(9)16(10)23)31-14-4-12(17(29)18(14)30)28-6-11(22)15-19(24)26-7-27-20(15)28/h3,6-7,12,14,17-18,25,29-30H,1-2,4-5H2,(H2,24,26,27)/t12-,14+,17+,18-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...

US Patent US10709709 (2020)


BindingDB Entry DOI: 10.7270/Q26113CC
More data for this
Ligand-Target Pair