Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50067832'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50067832 (3a,6-dimethyl-5,7-dioxo-(3'R,3aS,6R)-dispiro[perhy...) Show SMILES C[C@]12CC(=O)C3C(CCC(=O)[C@]3(C)C(O)=O)C1CC[C@@]21OCOC11COCO1 Show InChI InChI=1S/C20H26O8/c1-17-7-13(21)15-11(3-4-14(22)18(15,2)16(23)24)12(17)5-6-19(17)20(28-10-26-19)8-25-9-27-20/h11-12,15H,3-10H2,1-2H3,(H,23,24)/t11?,12?,15?,17-,18-,19+,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human Farnesyltransferase				J Med Chem 41: 4492-501 (1998) Article DOI: 10.1021/jm980356+ BindingDB Entry DOI: 10.7270/Q23779DQ
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