Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079668'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50079668 ((S)-2-(3-{[Bis-(4-nitro-benzyl)-amino]-methyl}-ben...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2ccc(cc2)[N+]([O-])=O)Cc2ccc(cc2)[N+]([O-])=O)c1)C(O)=O Show InChI InChI=1S/C27H28N4O7S/c1-39-14-13-25(27(33)34)28-26(32)22-4-2-3-21(15-22)18-29(16-19-5-9-23(10-6-19)30(35)36)17-20-7-11-24(12-8-20)31(37)38/h2-12,15,25H,13-14,16-18H2,1H3,(H,28,32)(H,33,34)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.				Bioorg Med Chem Lett 9: 1991-6 (1999) BindingDB Entry DOI: 10.7270/Q2ZG6RFB
					More data for this Ligand-Target Pair