Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50079672 ((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-methoxy-ben...) Show SMILES COc1ccc(CN(Cc2cnc[nH]2)Cc2cccc(c2)C(=O)N[C@@H](CCSC)C(O)=O)cc1 Show InChI InChI=1S/C25H30N4O4S/c1-33-22-8-6-18(7-9-22)14-29(16-21-13-26-17-27-21)15-19-4-3-5-20(12-19)24(30)28-23(25(31)32)10-11-34-2/h3-9,12-13,17,23H,10-11,14-16H2,1-2H3,(H,26,27)(H,28,30)(H,31,32)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.				Bioorg Med Chem Lett 9: 1991-6 (1999) BindingDB Entry DOI: 10.7270/Q2ZG6RFB
					More data for this Ligand-Target Pair