Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50079673 ((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-phenethyl-amin...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CN(CCc2ccccc2)Cc2cnc[nH]2)c1)C(O)=O Show InChI InChI=1S/C25H30N4O3S/c1-33-13-11-23(25(31)32)28-24(30)21-9-5-8-20(14-21)16-29(17-22-15-26-18-27-22)12-10-19-6-3-2-4-7-19/h2-9,14-15,18,23H,10-13,16-17H2,1H3,(H,26,27)(H,28,30)(H,31,32)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.				Bioorg Med Chem Lett 9: 1991-6 (1999) BindingDB Entry DOI: 10.7270/Q2ZG6RFB
					More data for this Ligand-Target Pair