Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50098014'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50098014 (CHEMBL169374 | N-(Cyano-methyl-methyl)-2-(2-phenyl...) Show SMILES CC(C#N)N(Cc1cccnc1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C25H22N4O/c1-18(15-26)29(17-19-8-7-13-27-16-19)24(30)14-22-21-11-5-6-12-23(21)28-25(22)20-9-3-2-4-10-20/h2-13,16,18,28H,14,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration required for the inhibitory activity against human Farnesyltransferase				Bioorg Med Chem Lett 11: 865-9 (2001) BindingDB Entry DOI: 10.7270/Q2F47PPX
					More data for this Ligand-Target Pair