Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50153771'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153771 (1-(3-Chloro-phenyl)-7-[(4-chloro-phenyl)-hydroxy-(...) Show SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)n(cc(C#N)c2=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C27H18Cl2N4O2/c1-32-16-31-14-25(32)27(35,18-5-8-20(28)9-6-18)19-7-10-23-24(11-19)33(15-17(13-30)26(23)34)22-4-2-3-21(29)12-22/h2-12,14-16,35H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bovine farnesyltransferase (FTase)				Bioorg Med Chem Lett 14: 5367-70 (2004) Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9
					More data for this Ligand-Target Pair