Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50153773'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153773 (4-(3-Chloro-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyr...) Show SMILES Cn1cncc1C(NC(=O)c1cn(C)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C25H20ClN5O2/c1-30-14-21(20(11-23(30)32)18-4-3-5-19(26)10-18)25(33)29-24(22-13-28-15-31(22)2)17-8-6-16(12-27)7-9-17/h3-11,13-15,24H,1-2H3,(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	685	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bovine farnesyltransferase (FTase)				Bioorg Med Chem Lett 14: 5367-70 (2004) Article DOI: 10.1016/j.bmcl.2004.08.012 BindingDB Entry DOI: 10.7270/Q2NS0TC9
					More data for this Ligand-Target Pair