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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50283065'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50283065
PNG
((E)-2-(2-{(S)-1-[(S)-1-((S)-1-Carboxy-2-hydroxy-et...)
Show SMILES [#6]-[#6]-[#8]-[#6](=O)-[#6](-[#6]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O)-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6]
Show InChI InChI=1S/C36H61N3O8/c1-10-47-36(46)28(18-17-27(9)16-12-15-26(8)14-11-13-23(2)3)19-20-31(41)39-32(25(6)7)34(43)37-29(21-24(4)5)33(42)38-30(22-40)35(44)45/h13,15,17,24-25,28-30,32,40H,10-12,14,16,18-22H2,1-9H3,(H,37,43)(H,38,42)(H,39,41)(H,44,45)/b26-15+,27-17+/t28?,29-,30-,32-/m0/s1
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Similars
Article
n/an/a>3.60E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ras Farnesyltransferase

Bioorg Med Chem Lett 4: 2107-2112 (1994)


Article DOI: 10.1016/S0960-894X(01)80111-6
BindingDB Entry DOI: 10.7270/Q2ZW1KTF
More data for this
Ligand-Target Pair