Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50283745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283745 ((S)-2-[5-((R)-2-Amino-3-mercapto-propionylamino)-2...) Show SMILES COc1ccc(CC(CCCNC(=O)[C@@H](N)CS)C(=O)N[C@@H](CCSC)C(O)=O)cc1 Show InChI InChI=1S/C21H33N3O5S2/c1-29-16-7-5-14(6-8-16)12-15(4-3-10-23-20(26)17(22)13-30)19(25)24-18(21(27)28)9-11-31-2/h5-8,15,17-18,30H,3-4,9-13,22H2,1-2H3,(H,23,26)(H,24,25)(H,27,28)/t15?,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase				Bioorg Med Chem Lett 4: 2775-2780 (1994) Article DOI: 10.1016/S0960-894X(01)80593-X BindingDB Entry DOI: 10.7270/Q21J99Q0
					More data for this Ligand-Target Pair