Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50284170'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284170 ((S)-2-{(S)-2-[(S)-2-((S)-3-Amino-4-mercapto-butyry...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)C[C@H](N)CS)C(C)C)C(O)=O Show InChI InChI=1S/C23H36N4O5S2/c1-14(2)20(27-19(28)12-16(24)13-33)22(30)26-18(11-15-7-5-4-6-8-15)21(29)25-17(23(31)32)9-10-34-3/h4-8,14,16-18,20,33H,9-13,24H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)(H,31,32)/t16-,17-,18-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase				Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6
					More data for this Ligand-Target Pair