Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50284171![]() ((S)-2-{(S)-2-[(S)-2-((R)-3-Mercapto-2-methylamino-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase | Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6 | |||||||||||
More data for this Ligand-Target Pair |