Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50284176'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284176 ((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propyl...) Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC[C@@H](N)CS)C(C)C)C(C)C)C(O)=O Show InChI InChI=1S/C18H36N4O4S2/c1-10(2)14(20-8-12(19)9-27)16(23)22-15(11(3)4)17(24)21-13(18(25)26)6-7-28-5/h10-15,20,27H,6-9,19H2,1-5H3,(H,21,24)(H,22,23)(H,25,26)/t12-,13+,14+,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase				Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6
					More data for this Ligand-Target Pair