Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50284182'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284182 ((S)-2-((S)-2-{[1-((R)-2-Amino-3-mercapto-propionyl...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C1(CCCCC1)NC(=O)[C@@H](N)CS)C(O)=O Show InChI InChI=1S/C24H36N4O5S2/c1-35-13-10-18(22(31)32)26-21(30)19(14-16-8-4-2-5-9-16)27-23(33)24(11-6-3-7-12-24)28-20(29)17(25)15-34/h2,4-5,8-9,17-19,34H,3,6-7,10-15,25H2,1H3,(H,26,30)(H,27,33)(H,28,29)(H,31,32)/t17-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration evaluated against P21ras Farnesyl transferase				Bioorg Med Chem Lett 4: 887-892 (1994) Article DOI: 10.1016/S0960-894X(01)80257-2 BindingDB Entry DOI: 10.7270/Q2N58MB6
					More data for this Ligand-Target Pair