Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50284953'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50284953 ((S)-2-[(S)-2-((S)-2-{[(S)-2-((R)-2,6-Diamino-hexan...) Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](S)NC(=O)[C@H](N)CCCCN)C(O)=O Show InChI InChI=1S/C28H46N6O6S2/c1-17(2)22(34(3)27(38)26(41)33-23(35)19(30)12-8-9-14-29)25(37)32-21(16-18-10-6-5-7-11-18)24(36)31-20(28(39)40)13-15-42-4/h5-7,10-11,17,19-22,26,41H,8-9,12-16,29-30H2,1-4H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20+,21+,22+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl transferase (FTase) of rat brain				Bioorg Med Chem Lett 5: 1779-1784 (1995) Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH
					More data for this Ligand-Target Pair