Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50289150![]() (Acetic acid (7E,11E)-(1S,2R,4R,14S,15R)-4,8,12-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Kinetic parameter for inihibiton of farnesyl protein transferase | Bioorg Med Chem Lett 6: 909-912 (1996) Article DOI: 10.1016/0960-894X(96)00142-4 BindingDB Entry DOI: 10.7270/Q2VT1S3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50289150![]() (Acetic acid (7E,11E)-(1S,2R,4R,14S,15R)-4,8,12-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inihibtion of recombinant human farnesyl protein transferase | Bioorg Med Chem Lett 6: 909-912 (1996) Article DOI: 10.1016/0960-894X(96)00142-4 BindingDB Entry DOI: 10.7270/Q2VT1S3W | |||||||||||
More data for this Ligand-Target Pair |